new Delhi. India is taking a serious step forward with the prevention of Kovid-19. Its eyes are on all the vaccines produced in the world. Vaccine trials in India are also in the third phase. However, it is difficult to say how long the vaccine will be available in India. There are only speculations about this. Even after this, India has booked vaccines through various means to provide its dose to its countrymen.
Novavax: India has reserved one billion doses of vaccine. She is currently undergoing Phase III testing and is being tested by 10,000 people in the UK. A large-scale trial could begin this month. If the test is successful, the vaccine will become available to people by the latter part of the year. In September, Novavax and Serum Institute have tied up to produce two billion doses per year.
Sputnik-5: India has also tied up with Russia’s Gamalaya Research Institute for the Sputnik-5 vaccine. It has been claimed that Sputnik-5 is 92% effective.
This is how the RNA vaccine will work: Scientists take the virus’s genetic code, which shows what will develop from the cells. They then coat it in lipids, so that it can easily enter the cells of the body. By injecting the patient, RNAvaccine enters cells and induces them to produce corona virus spike proteins. This signals the immune system to produce antibodies and activate the T-cell, thereby eliminating the infected cells. In this way, the patient fights the corona virus and destroys antibodies and T-cell infection.
Protein-based vaccine more suitable: Scientist Kovid-19 can have many aspects of good vaccine, these include safety, price, convenience of transportation, etc. Considering these aspects, scientists consider the protein-based corona vaccine more suitable for India.
Satyajit Rath, an immunologist at the National Institute of Immunology (NIII), New Delhi, says, “The vaccines of American Pfizer-BioNotech and Russian Sputnik-5 have to be kept at extremely low temperatures. These are mRNA, DNA and vector based vaccines. A protein-based vaccine such as Novavax would not require such a low temperature for storage. Storing the vaccine in low temperatures in India will be a major challenge.
Professor Raghavan Vardharajan of the Indian Institute of Science, Bangalore, also seems to agree with the chariot. Scientists believe that the same vaccines would be more suitable for India, which can be stored at 4-10 ° C and possible to transport them in liquid form. The vaccines of Johnson & Johnson, AstraZeneca and Sanofi etc. are those which will not require deep freezing.
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